Shingrix

GlaxoSmithKline (GSK)

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Description

Shingrix is a vaccine used to prevent shingles (herpes zoster) in adults. It contains an antigen derived from the varicella-zoster virus combined with an adjuvant system to boost the immune response.

Target Diseases

  • Shingles (Herpes Zoster) and associated complications such as postherpetic neuralgia (PHN).

Dosage Schedule

2 doses, administered intramuscularly. Second dose is given 2-6 months after the first dose.

Possible Side Effects

  • Common: Pain
  • redness
  • and swelling at the injection site
  • muscle pain
  • fatigue
  • headache
  • fever
  • gastrointestinal symptoms (nausea
  • diarrhea). Rare: Allergic reactions (e.g.
  • rash
  • swelling of the face).

Contraindications

  • Severe allergic reactions to any component of the vaccine. Currently having an active herpes zoster infection. Pregnancy or breastfeeding (consult a doctor before administration).

Additional Information

  • Shingrix has been shown to provide strong and long-lasting protection against shingles and its complications
  • with over 90% efficacy in clinical trials. Ideal for adults with weakened immune systems or chronic conditions
  • as shingles can cause severe complications in these groups. Offers superior protection compared to the live shingles vaccine (Zostavax).

Storage Requirements

  • Store in a refrigerator at 2°C to 8°C. Do not freeze. Protect from light.
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